Invitrogen™ Factor VIII Monoclonal Antibody (9035)

Catalog No.	Quantity
01-676-483	100 μg

Catalog No. 01-676-483 Supplier Invitrogen™ Supplier No. MA143037

Description

Rat Monoclonal Antibody

MA1-43037 detects Factor VIII in mouse samples. MA1-43037 has successfully been used in Western blot and ELISA applications. MA1-43037 was derived from mouse factor VIII.

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Specifications

• Antigen: Factor VIII
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 9035
• Concentration: 8.1 mg/mL
• Conjugate: Unconjugated
• Formulation: 50% water with 50% glycerol and no preservative
• Gene: F8
• Gene Accession No.: Q06194
• Gene Alias: AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
• Gene Symbols: F8
• Host Species: Rat
• Immunogen: Mouse Factor VIII.
• Purification Method: SDS-PAGE
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14069
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid