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  6. Factor VIII Related Antigen/von Willebrand Factor Ab-2 Mouse Monoclonal Antibody, Epredia™

Factor VIII Related Antigen/von Willebrand Factor Ab-2 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS722RQ Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
12 mL
Form:
Concentrated
Prediluted
Ready-to-Use
Concentration:
1mg/mL
200μg/mL
Prediluted
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Catalog No. Quantity Form Concentration
MS722RQ 12 mL Ready-to-Use Prediluted
MS722P1ABX 100 μL Concentrated 1mg/mL
MS722PABX 200 μL Concentrated 1mg/mL
MS722P 1 mL Concentrated 200μg/mL
MS722P0 100 μL Concentrated 200μg/mL
MS722P1 500 μL Concentrated 200μg/mL
MS722R1 1 mL Prediluted Prediluted
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Catalog No. MS722RQ Supplier Epredia Supplier No. MS722RQ

Description

Ensure accurate, reproducible results in immunohistochemistry experiments.

Factor VIII related antigen or von Willebrand factor is a multimeric glycoprotein, which binds to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. It is synthesized by endothelial cells and stored in the Weibel-Palade granules. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. von Willebrand factor is one of the most useful markers to identify endothelial (or megakaryocytic) lineage of neoplasms. As not all endothelial cells synthesize/store this molecule, about 30% of tumors of vascular origin fail to stain for factor VIII related antigen, regardless of whether they are benign or malignant. Staining for factor VIII related antigen has also been used to measure angiogenesis, an indicator of tumor recurrence.

Host Species: Mouse

Clone: F8/86

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Partially purified von Willebrand factor from human placenta

Molecular Weight: 270 kDa

Positive Control: Blood vessels in tonsil or intestine

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen Factor VIII Related Antigen/von Willebrand Factor Ab-2
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone F8/86
Concentration Prediluted
Conjugate Unconjugated
Host Species Mouse
Immunogen Partially purified von Willebrand factor from human placenta
Quantity 12 mL
Regulatory Status IVD
Research Discipline Hematopoietic
Primary or Secondary Primary
Form Ready-to-Use
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