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Invitrogen™ Factor X/Xa (Calcium-dependent) Monoclonal Antibody (CaFX-50), Biotin
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Catalog No. PIMA517644
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100 μg
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PIMA517644 100 μg
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Catalog No. PIMA517644 Supplier Invitrogen™ Supplier No. MA517644
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Description

Mouse Monoclonal Antibody

This antibody is specific for Human Platelet Factors X and Xa in the presence of 5-10 mM CaCl2.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Factor X/Xa (Calcium-dependent)
Applications ELISA, Western Blot
Classification Monoclonal
Clone CaFX-50
Concentration 0.1 mg/mL
Conjugate Biotin
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene F10
Gene Accession No. P00742
Gene Alias Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Gene Symbols F10
Host Species Mouse
Immunogen Human Factor X purified from the supernatant of thrombin activated platelets.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2159
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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