Factor X Mouse anti-Human, Clone: 3D3F11, Proteintech

Catalog No.	Quantity
50-173-7160	150 μL

Catalog No. 50-173-7160 Supplier Proteintech Group Inc Supplier No. 667531IG150UL

Description

Mouse Monoclonal Antibody

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

Specifications

• Antigen: Factor X
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 3D3F11
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: F10
• Gene Accession No.: P00742
• Gene Alias: coagulation factor X, F10, Factor X, FX, FXA, Stuart factor, Stuart Prower factor
• Gene Symbols: F10
• Host Species: Mouse
• Immunogen: Factor X Fusion Protein Ag11664
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2159
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1