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Invitrogen™ Factor X/Xa Polyclonal Antibody
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Catalog No. PIPA143061
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PIPA143061 1 mg
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Catalog No. PIPA143061 Supplier Invitrogen™ Supplier No. PA143061
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Description

Sheep Polyclonal Antibody

PA1-43061 detects Factor X in mouse samples. PA1-43061 has successfully been used in Western blot and ELISA applications. PA1-43061 was derived from mouse factor X.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Factor X/Xa
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 25 mg/mL
Conjugate Unconjugated
Formulation 50% water with 50% glycerol and no preservative
Gene F10
Gene Accession No. O88947, Q63207
Gene Alias Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Gene Symbols F10
Host Species Sheep
Immunogen Murine Factor X.
Purification Method SDS-PAGE
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14058, 29243
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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