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Invitrogen™ Factor XI Polyclonal Antibody

Catalog No. PIPA585390
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100 μL
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Catalog No. Quantity
PIPA585390 100 μL
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Catalog No. PIPA585390 Supplier Invitrogen™ Supplier No. PA585390

Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Dog (88%), Rabbit (92%), Bovine (88%). Positive Control: A549, HeLa, human plasma. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Factor XI
Applications Western Blot
Classification Polyclonal
Concentration 0.67 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene F11
Gene Accession No. P03951, Q91Y47
Gene Alias 1600027G01Rik; AI503996; Cf11; Coagulation factor XI; Coagulation factor XIa heavy chain; Coagulation factor XIa light chain; F11; FXI; LRRGT00086; plasma thromboplastin antecedent; PTA
Gene Symbols F11
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Factor XI. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109821, 2160
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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