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        Tocris Bioscience™ FAK Inhibitor 14
    
    
    
    
    
    
    
    
    
    
        
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                                Quantity:
                            
                        
                        
                            
                                10 mg
                            
                        
                            
                                50 mg
                            
                        
                    Description
FAK Inhibitor 14 is a selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. FAK Inhibitor 14 prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. FAK Inhibitor 14 exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo.
                        
                        
                        
                        
                        
                        
                        
                        
                        
                    
                
                
                    
                
                
    
                
    
            Specifications
Specifications
| Quantity | 10 mg | 
| Formula Weight | 284.01 | 
| Purity | >98% | 
| Molecular Weight (g/mol) | 284.006 | 
| Chemical Name or Material | FAK Inhibitor 14 | 
Safety and Handling
| Recommended Storage | Desiccate at Room Temperature | 
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