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  5. Tocris Bioscience™ FAK Inhibitor 14

Tocris Bioscience™ FAK Inhibitor 14
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Catalog No. 341410
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Catalog No. Quantity
34-141-0 10 mg
34-145-0 50 mg
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Catalog No. 34-141-0 Supplier Tocris Bioscience™ Supplier No. 3414/10
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Description

Selective FAK inhibitor

FAK Inhibitor 14 is a selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. FAK Inhibitor 14 prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. FAK Inhibitor 14 exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo.

Chemical Identifiers

CAS 4506-66-5
Molecular Formula C6H14Cl4N4

Specifications

Quantity 10 mg
Formula Weight 284.01
Purity >98%
Molecular Weight (g/mol) 284.006
Chemical Name or Material FAK Inhibitor 14

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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