Invitrogen™ FAM122A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563338

Catalog No. PIPA563338

Description

Immunogen sequence: AQLSDPGVCV SSDTLDGNSS SAGSSCNSPA KVSTTTDSPV SPAQAASPFI PLDE Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 96%.

Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin- mediated proteolysis of WEE1, thereby releasing G2/M checkpoint.

Specifications

• Antigen: FAM122A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM122A
• Gene Alias: C9orf42; FAM122A; family with sequence similarity 122A; protein FAM122A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116224
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96E09
• Gene Symbols: FAM122A
• Immunogen: Recombinant protein corresponding to Human FAM122A. Recombinant protein control fragment (Product #RP-101581).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG