Invitrogen™ FAM122B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113059

Catalog No. PIPA5113059

Description

FAM122B Polyclonal Antibody for Western Blot, IHC (P), ELISA

FAM122B (Family with Sequence Similarity 122 Member B) is a gene located on chromosome 9 that encodes a protein involved in cellular signaling and regulation. FAM122B is known to interact with protein phosphatase 2A (PP2A), a critical enzyme in multiple signaling pathways, thereby impacting various cellular functions such as growth, division, and apoptosis. This interaction is pivotal for the modulation of PP2A activity, which in turn influences numerous downstream signaling processes. Studies have indicated that FAM122B may play a role in cancer biology, particularly in the regulation of oncogenic pathways. Dysregulation of FAM122B expression has been observed in certain cancers, suggesting its potential involvement in tumor progression and as a biomarker for diagnosis or prognosis. Furthermore, the gene's expression patterns indicate its importance in normal cellular homeostasis and the maintenance of cellular signaling balance.

Specifications

• Antigen: FAM122B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM122B
• Gene Alias: 4632404H22Rik; AI256344; erg-3; ets-related; FAM122B; family with sequence similarity 122, member B; family with sequence similarity 122B; p55; protein FAM122B; RP11-308B5.5; SPACIA2; synoviocyte proliferation associated in collagen-induced arthritis 2; TMPRSS2/ERG fusion
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 159090, 78755
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q6NZE7, Q7Z309
• Gene Symbols: FAM122B
• Immunogen: Recombinant Human Protein FAM122B protein (2-247AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov