Invitrogen™ FAM126A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534761

Catalog No. PIPA534761

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (91%), Rat (89%), Rhesus Monkey (98%). IHC notes, Requires antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.

Specifications

• Antigen: FAM126A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM126A
• Gene Alias: AB030242; down regulated by Ctnnb1, a; down-regulated by CTNNB1 protein A; down-regulated by Ctnnb1, a; DRCTNNB1A; Fam126a; family with sequence similarity 126 member A; family with sequence similarity 126, member A; HCC; HLD5; HYCC1; Hyccin; Protein FAM126A; RGD1562906
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84652, 84668
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6P9N1, Q9BYI3
• Gene Symbols: FAM126A
• Immunogen: Recombinant protein encompassing a sequence within the center region of human FAM126A. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov