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Invitrogen™ FAM173B Polyclonal Antibody
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Catalog No. PIPA5121095
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100 μL
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PIPA5121095 100 μL
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Catalog No. PIPA5121095 Supplier Invitrogen™ Supplier No. PA5121095
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Description

Rabbit Polyclonal Antibody

Positive test controls include: A-549, BT-474, HL-60, Mouse liver, Mouse kidney, Mouse heart, Rat brain. The target is usually found in the following locations: Membrane, Single-pass membrane protein. Immunogen sequence: MEGGGGIPLE TLKEESQSRH VLPASFEVNS LQKSNWGFLL TGLVGGTLVA VYAVATPFVT PALRKVCLPF VPATTKQIEN VVKMLRCRRG SLVDIGSGDG RIVIAAAKKG FTAVGYELNP WLVWYSRYRA WREGVHGSAK FYISDLWKVT FSQYSNVVIF GVPQMMLQLE KKLERELEDD ARVIACRFPF PHWTPDHVTG EGIDTVWAYD ASTFRGREKR PCTSMHFQLP IQA.

FAM173B is a 233 amino acid single-pass membrane protein that is encoded by a gene that maps to human chromosome 5, which makes up about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM173B
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.24 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene FAM173B
Gene Accession No. Q6P4H8, Q9D1Z3
Gene Alias A930016P21Rik; AA987072; ATP synthase subunit C lysine N-methyltransferase; Atpsckmt; FAM173B; family with sequence similarity 173 member B; family with sequence similarity 173, member B; hFAM173B; JS-2; mFam173b; protein FAM173B; Protein N-lysine methyltransferase FAM173B; RGD1560629
Gene Symbols FAM173B
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FAM173B (NP_954584.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 134145, 499561, 68073
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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