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Invitrogen™ FAM178A Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA566091
Description
Immunogen sequence: ASKYLAKGTNI YVPSSYHLPK EMKSLKKKHR SPERRKSLFI HENNEKNDRD RGKTNADSKK QTTVAEADIF NNSSRSLS Highest antigen sequence identity to the following orthologs - mouse 71%, rat 71%.
Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).
Specifications
FAM178A | |
Polyclonal | |
Unconjugated | |
SLF2 | |
C10orf6; FAM178A; family with sequence similarity 178, member A; protein FAM178A; SLF2; Smc5/6 localization factor 1; SMC5-SMC6 complex localization factor 2; SMC5-SMC6 complex localization factor protein 2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
55719 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry | |
0.3 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q8IX21 | |
SLF2 | |
Recombinant Human FAM178A. Recombinant protein control fragment (Product #RP-105077). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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