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Invitrogen™ FAM178A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566091

Catalog No. PIPA566091


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Description

Description

Immunogen sequence: ASKYLAKGTNI YVPSSYHLPK EMKSLKKKHR SPERRKSLFI HENNEKNDRD RGKTNADSKK QTTVAEADIF NNSSRSLS Highest antigen sequence identity to the following orthologs - mouse 71%, rat 71%.

Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

FAM178A
Polyclonal
Unconjugated
SLF2
C10orf6; FAM178A; family with sequence similarity 178, member A; protein FAM178A; SLF2; Smc5/6 localization factor 1; SMC5-SMC6 complex localization factor 2; SMC5-SMC6 complex localization factor protein 2
Rabbit
Antigen affinity chromatography
RUO
55719
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry
0.3 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q8IX21
SLF2
Recombinant Human FAM178A. Recombinant protein control fragment (Product #RP-105077).
100 μL
Primary
Human
Antibody
IgG
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