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Invitrogen™ FAM178A Polyclonal Antibody
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Catalog No. PIPA566091
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100 μL
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PIPA566091 100 μL
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Catalog No. PIPA566091 Supplier Invitrogen™ Supplier No. PA566091
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ASKYLAKGTNI YVPSSYHLPK EMKSLKKKHR SPERRKSLFI HENNEKNDRD RGKTNADSKK QTTVAEADIF NNSSRSLS Highest antigen sequence identity to the following orthologs - mouse 71%, rat 71%.

Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM178A
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLF2
Gene Accession No. Q8IX21
Gene Alias C10orf6; FAM178A; family with sequence similarity 178, member A; protein FAM178A; SLF2; Smc5/6 localization factor 1; SMC5-SMC6 complex localization factor 2; SMC5-SMC6 complex localization factor protein 2
Gene Symbols SLF2
Host Species Rabbit
Immunogen Recombinant Human FAM178A. Recombinant protein control fragment (Product #RP-105077).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55719
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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