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Invitrogen™ FAM213A Polyclonal Antibody
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Catalog No. PIPA552640
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100 μL
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Catalog No. Quantity
PIPA552640 100 μL
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Catalog No. PIPA552640 Supplier Invitrogen™ Supplier No. PA552640
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NTDVFLSKPQ KAALEYLEDI DLKTLEKEPR TFKAKELWEK NGAVIMAVRR PGCFLCREEA ADLSSLKSML DQLGVPLYAV VKEHIRTEVK DFQPYFKGE Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.

Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM213A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FAM213A
Gene Accession No. Q6AXX6, Q9BRX8
Gene Alias C10orf58; Fam213a; family with sequence similarity 213 member A; family with sequence similarity 213, member A; Pamm; peroxiredoxin (PRX)-like 2 activated in M-CSF stimulated monocytes; peroxiredoxin-like 2 activated in M-CSF stimulated monocytes; Peroxiredoxin-like 2A; PRO2290; Protein PAMM; PRXL2A; PSEC0139; Redox-regulatory protein FAM213A; redox-regulatory protein PAMM; RGD1309676; Shp1; similar to RIKEN cDNA 5730469M10; sperm head protein 1; UNQ611/PRO1198; UPF0765 protein C10orf58; UPF0765 protein C10orf58 homolog
Gene Symbols FAM213A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FAM213A. Recombinant protein control fragment (Product #RP-90168).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361118, 84293
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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