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Invitrogen™ FAM35A Polyclonal Antibody
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Catalog No. FEPA5144862
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100 μL
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Catalog No. Quantity
FEPA5144862 100 μL
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Catalog No. FEPA5144862 Supplier Invitrogen™ Supplier No. PA5144862
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ISTDTEFLSI ITSSQVAFLA QKKDKRRSPV NKGNVNMETE PKASYGEIRI PEENSIQLDG FTEAYESGQN QAYSLEL Antigen sequence identity: Mouse 49%; Rat 54%.

Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM35A
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FAM35A
Gene Accession No. Q86V20
Gene Alias bA163M19.1; FAM35A; FAM35A1; family with sequence similarity 35 member A; family with sequence similarity 35, member A; protein FAM35A; RINN1-REV7-interacting novel NHEJ regulator 2; RINN2; Shield complex subunit 2; Shieldin complex subunit 2; SHLD2
Gene Symbols FAM35A
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 236-312. Recombinant protein control fragment (Product #RP-109943).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54537
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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