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Invitrogen™ FAM35A Polyclonal Antibody
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Catalog No. PIPA5114103
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100 μL
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PIPA5114103 100 μL
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Catalog No. PIPA5114103 Supplier Invitrogen™ Supplier No. PA5114103
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PDLSGHFLAN CMNRHVHVKD DFVRSVSETQ NIESQKIHSS RLSDITSSNM For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Human: 100%.

Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM35A
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene FAM35A
Gene Accession No. Q86V20
Gene Alias bA163M19.1; FAM35A; FAM35A1; family with sequence similarity 35 member A; family with sequence similarity 35, member A; protein FAM35A; RINN1-REV7-interacting novel NHEJ regulator 2; RINN2; Shield complex subunit 2; Shieldin complex subunit 2; SHLD2
Gene Symbols FAM35A
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N terminal region of human FAM35A (aa 71-120).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54537
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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