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Invitrogen™ FAM3B Polyclonal Antibody
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Catalog No. PIPA542794
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100 μL
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PIPA542794 100 μL
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Catalog No. PIPA542794 Supplier Invitrogen™ Supplier No. PA542794
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Description

Rabbit Polyclonal Antibody

Peptide sequence: HWTPCPSDTY AYRLLSGGGR SKYAKICFED NLLMGEQLGN VARGINIAIV Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 86%.

FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM3B
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene FAM3B
Gene Accession No. P58499
Gene Alias 21-Feb; 2-21; 9030624C24Rik; C21orf11; C21orf76; cytokine-like protein 2-21; D16Jhu19e; D21M16SJHU19e; FAM3 metabolism regulating signaling molecule B; Fam3b; family with sequence similarity 3 member B; family with sequence similarity 3, member B; ORF9; pancreatic derived factor; pancreatic-derived factor; PANDER; PRED44; Protein FAM3B; RGD1311662; UNQ320/PRO365
Gene Symbols FAM3B
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human FAM3B.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54097
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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