Invitrogen™ FAM3B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553397

Catalog No. PIPA553397

Description

Immunogen sequence: TPCPSDTYAY RLLSGGGRSK YAKICFEDNL LMGEQLGNVA RGINIAIVNY VTGNVTATRC FDMYEGDNSG PMTKFIQSAA PKSLLFMVTY DDGSTRLNND AKNAIEALGS KEIRN Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 75%.

FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events.

Specifications

• Antigen: FAM3B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM3B
• Gene Alias: 21-Feb; 2-21; 9030624C24Rik; C21orf11; C21orf76; cytokine-like protein 2-21; D16Jhu19e; D21M16SJHU19e; FAM3 metabolism regulating signaling molecule B; Fam3b; family with sequence similarity 3 member B; family with sequence similarity 3, member B; ORF9; pancreatic derived factor; pancreatic-derived factor; PANDER; PRED44; Protein FAM3B; RGD1311662; UNQ320/PRO365
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54097
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P58499
• Gene Symbols: FAM3B
• Immunogen: Recombinant protein corresponding to Human FAM3B. Recombinant protein control fragment (Product #RP-90535).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG