FAM3B Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA572488

Catalog No. PIPA572488

Description

FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events.

Specifications

• Antigen: FAM3B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM3B
• Gene Alias: C21orf11; Cytokine like protein 2 21; Cytokine-like protein 2-21; Fam3b; FAM3B; Pancreatic-derived factor; PANDER; PRED44; Protein FAM3B
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 54097
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.67 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P58499
• Gene Symbols: FAM3B
• Immunogen: KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human FAM3B
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG