Invitrogen™ FAM62B Monoclonal Antibody (C4-D0)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA542563

Catalog No. PIMA542563

Description

Positive Control: Siha cell lysate, THP-1 cell lysate, human colon carcinoma tissue. Subcellular Location: Cell membrane, Endoplasmic reticulum, Membrane.

Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:27044890). [UniProt].

Specifications

• Antigen: FAM62B
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: A0FGR8
• Gene Symbols: ESYT2
• Immunogen: Recombinant protein within human FAM62B aa 300-550.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: C4-D0
• Conjugate: Unconjugated
• Gene: ESYT2
• Gene Alias: 2410017M09Rik; 4921504I16Rik; chr2 synaptotagmin; CHR2SYT; D12Ertd551e; ESYT2; E-Syt2; extended synaptotagmin 2; extended synaptotagmin like protein 2; extended synaptotagmin protein 2; extended synaptotagmin-2; extended synaptotagmin-like protein 2; Fam62b; family with sequence similarity 62 (C2 domain containing), member B; family with sequence similarity 62, member B; KIAA1228; RGD1565705
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 57488
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid