Invitrogen™ FAM65A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595803

Catalog No. PIPA595803

Description

Immunogen sequence: LSLRQPGLAE AVCVKFLEDA LGQKLPRRPQ PGPGEQLTVF QFWSFVETLD SPTMEAYVTE TAEEVLLVRN LNSDDQAVVL KALRLAPEGR LRRDGLRALS SLLVHGNNKV MAAVSTQLRS LSLGPTFRER ALLCFLDQLE DEDVQTRVAG CLALGCIKAP EGIEPLVYLC QTDTEAVREA ARQSLQQCGE EGQSAHRRLE ESLDALPRIF GPGSMASTAF; Positive Samples: Mouse kidney; Cellular Location: Cytoplasm.

Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt].

Specifications

• Antigen: FAM65A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RIPOR1
• Gene Alias: 2310066E14Rik; AI837433; Fam65a; family with sequence similarity 65 member A; family with sequence similarity 65, member A; FLJ13725; Kiaa1930; protein FAM65A; Rho family-interacting cell polarization regulator 1; RIPOR1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 75687
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.7 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q68FE6
• Gene Symbols: RIPOR1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1004-1223 of human FAM65A (NP_0011804511).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov