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Invitrogen™ FAM65A Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA595803
Description
Immunogen sequence: LSLRQPGLAE AVCVKFLEDA LGQKLPRRPQ PGPGEQLTVF QFWSFVETLD SPTMEAYVTE TAEEVLLVRN LNSDDQAVVL KALRLAPEGR LRRDGLRALS SLLVHGNNKV MAAVSTQLRS LSLGPTFRER ALLCFLDQLE DEDVQTRVAG CLALGCIKAP EGIEPLVYLC QTDTEAVREA ARQSLQQCGE EGQSAHRRLE ESLDALPRIF GPGSMASTAF; Positive Samples: Mouse kidney; Cellular Location: Cytoplasm.
Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt].
Specifications
FAM65A | |
Polyclonal | |
Unconjugated | |
RIPOR1 | |
2310066E14Rik; AI837433; Fam65a; family with sequence similarity 65 member A; family with sequence similarity 65, member A; FLJ13725; Kiaa1930; protein FAM65A; Rho family-interacting cell polarization regulator 1; RIPOR1 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
75687 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
1.7 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
Q68FE6 | |
RIPOR1 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1004-1223 of human FAM65A (NP_0011804511). | |
100 μL | |
Primary | |
Mouse | |
Antibody | |
IgG |
Safety and Handling
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