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Invitrogen™ FAM73A Polyclonal Antibody
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Catalog No. PIPA553611
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100 μL
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PIPA553611 100 μL
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Catalog No. PIPA553611 Supplier Invitrogen™ Supplier No. PA553611
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QEEFEATLGA SDPNSLADDI DKDTDITMKG NVEDFGLRDT LSIASTDSFA SAAELAEHRE VRHTYSLESL CHCPFYEEAM HLVEEGKIYS RVLRTEMLEC LGDSDFLAKL HCIRQAFQVI LSESANR Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 63%.

The FAM73A gene, also known as Family With Sequence Similarity 73 Member A, is located on chromosome 2q33.3. This gene encodes a protein embedded in cellular membranes and is recognized for its involvement in various cellular processes including signal transduction and cell communication. FAM73A has been observed to play a significant role in the regulation of cancer stem cell-like properties, particularly in gastric cancer, where its circular RNA form (circFAM73A) has been implicated in tumor progression. Additionally, FAM73A is involved in iron homeostasis and resistance mechanisms within the cell, suggesting its participation in broader metabolic and stress response pathways. The gene includes multiple exons and is subject to alternative splicing, which yields various transcript variants, enhancing its functional diversity within different cellular contexts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM73A
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MIGA1
Gene Accession No. Q8NAN2
Gene Alias FAM73A; family with sequence similarity 73 member A; family with sequence similarity 73, member A; MIGA1; Mitoguardin 1; mitoguardin-1; protein FAM73A
Gene Symbols MIGA1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FAM73A. Recombinant protein control fragment (Product #RP-90528).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 374986
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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