Invitrogen™ FAM83D Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140100

Catalog No. PIPA5140100

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: ASSTGSPASI RTTDFHNPGY PKYLGTPHLE LYLSDSLRNL NKERQFHFAG IRSRLNHMLA MLSRRTLFTE NHLGLHSGNF S.

Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.

Specifications

• Antigen: FAM83D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM83D
• Gene Alias: 2310007D09Rik; BB104611; C20orf129; CHICA; dJ616B8.3; FAM83D; family with sequence similarity 83 member D; family with sequence similarity 83, member D; mitotic spindle protein CHICA; protein FAM83D; RGD1565583; spindle protein CHICA
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81610
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H4H8
• Gene Symbols: FAM83D
• Immunogen: Recombinant protein corresponding to Human FAM83D. Recombinant protein control fragment (Product #RP-108985).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG