Invitrogen™ FAM83D Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA571098

Catalog No. PIPA571098

Description

This target displays homology in the following species: Horse: 79%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 79%.

Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.

Specifications

• Antigen: FAM83D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAM83D
• Gene Alias: 2310007D09Rik; BB104611; C20orf129; CHICA; dJ616B8.3; FAM83D; family with sequence similarity 83 member D; family with sequence similarity 83, member D; mitotic spindle protein CHICA; protein FAM83D; RGD1565583; spindle protein CHICA
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81610
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9H4H8
• Gene Symbols: FAM83D
• Immunogen: synthetic peptide directed towards the C-terminal region of human FAM83D.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG