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Invitrogen™ FAM89B Polyclonal Antibody
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Catalog No. PA550410
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100 μL
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PA550410 100 μL
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Catalog No. PA550410 Supplier Invitrogen™ Supplier No. PA550410
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total FAM89B protein.

Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta. Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM89B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Fam89b
Gene Accession No. Q8N5H3
Gene Alias 1110021A21Rik; C184L ORF2 protein; C184m; C184M protein; FAM89B; family with sequence similarity 89 member B; family with sequence similarity 89, member B; Leucine repeat adapter protein 25; leucine repeat adaptor protein 25; Lrap25; Mammary tumor virus receptor 2; mammary tumor virus receptor homolog 1; MMTV; MMTV receptor; MTVR; MTVR1; Mtvr2; protein FAM89B
Gene Symbols Fam89b
Host Species Rabbit
Immunogen Full length fusion protein of Human FAM89B.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23625
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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