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Invitrogen™ FAM89B Polyclonal Antibody
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Catalog No. PIPA561367
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100 μL
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PIPA561367 100 μL
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Catalog No. PIPA561367 Supplier Invitrogen™ Supplier No. PA561367
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RKEMLWGLYE SIQDYKHLCQ DLSFCQDLSS SLHSDSSYPP DAGLS Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 89%.

Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta. Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM89B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Fam89b
Gene Accession No. Q8N5H3
Gene Alias 1110021A21Rik; C184L ORF2 protein; C184m; C184M protein; FAM89B; family with sequence similarity 89 member B; family with sequence similarity 89, member B; Leucine repeat adapter protein 25; leucine repeat adaptor protein 25; Lrap25; Mammary tumor virus receptor 2; mammary tumor virus receptor homolog 1; MMTV; MMTV receptor; MTVR; MTVR1; Mtvr2; protein FAM89B
Gene Symbols Fam89b
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FAM89B. Recombinant protein control fragment (Product #RP-100459).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23625
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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