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Invitrogen™ FAM89B Polyclonal Antibody
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Catalog No. PIPA572996
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100 μg
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PIPA572996 100 μg
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Catalog No. PIPA572996 Supplier Invitrogen™ Supplier No. PA572996
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Rabbit Polyclonal Antibody

FAM89B Polyclonal Antibody for Western Blot

Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta. Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAM89B
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Fam89b
Gene Accession No. Q9QUI1
Gene Alias 1110021A21Rik; C184L ORF2 protein; C184m; C184M protein; FAM89B; family with sequence similarity 89 member B; family with sequence similarity 89, member B; Leucine repeat adapter protein 25; leucine repeat adaptor protein 25; Lrap25; Mammary tumor virus receptor 2; mammary tumor virus receptor homolog 1; MMTV; MMTV receptor; MTVR; MTVR1; Mtvr2; protein FAM89B
Gene Symbols Fam89b
Host Species Rabbit
Immunogen Reacts with residues 152-163 of the 20 kDa MMTV-R.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17826
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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