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Invitrogen™ FAN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521512

Catalog No. PIPA521512


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Description

Description

Recommended positive controls: FAN tansfected 293T cell. Predicted reactivity: Mouse (93%), Rat (91%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

FAN
Polyclonal
Unconjugated
NSMAF
AA959567; C630007J05; factor associated with neutral sphingomyelinase activation; Factor associated with N-SMase activation; FAN; GRAMD5; neutral sphingomyelinase (N-SMase) activation associated factor; neutral sphingomyelinase activation associated factor; NSMAF; Protein FAN
Rabbit
Antigen affinity chromatography
RUO
8439
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.93 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q92636
NSMAF
Recombinant fragment corresponding to a region within amino acids 262 and 570 of FAN (Uniprot ID#Q92636).
100 μL
Primary
Human
Antibody
IgG
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