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Invitrogen™ FAN Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA521512
Description
Recommended positive controls: FAN tansfected 293T cell. Predicted reactivity: Mouse (93%), Rat (91%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
Specifications
FAN | |
Polyclonal | |
Unconjugated | |
NSMAF | |
AA959567; C630007J05; factor associated with neutral sphingomyelinase activation; Factor associated with N-SMase activation; FAN; GRAMD5; neutral sphingomyelinase (N-SMase) activation associated factor; neutral sphingomyelinase activation associated factor; NSMAF; Protein FAN | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
8439 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.93 mg/mL | |
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
Q92636 | |
NSMAF | |
Recombinant fragment corresponding to a region within amino acids 262 and 570 of FAN (Uniprot ID#Q92636). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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