Invitrogen™ FAN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521512

Catalog No. PIPA521512

Description

Recommended positive controls: FAN tansfected 293T cell. Predicted reactivity: Mouse (93%), Rat (91%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: FAN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NSMAF
• Gene Alias: AA959567; C630007J05; factor associated with neutral sphingomyelinase activation; Factor associated with N-SMase activation; FAN; GRAMD5; neutral sphingomyelinase (N-SMase) activation associated factor; neutral sphingomyelinase activation associated factor; NSMAF; Protein FAN
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8439
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.93 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q92636
• Gene Symbols: NSMAF
• Immunogen: Recombinant fragment corresponding to a region within amino acids 262 and 570 of FAN (Uniprot ID#Q92636).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov