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Invitrogen™ FANCD2 Monoclonal Antibody (6)
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Catalog No. PIMA123347
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100 μL
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Catalog No. Quantity
PIMA123347 100 μL
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Catalog No. PIMA123347 Supplier Invitrogen™ Supplier No. MA123347
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Description

Mouse Monoclonal Antibody

MA1-23347 detects FANCD2 in Human samples.

FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability. It promotes accurate and efficient pairing of homologs during meiosis. FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing. It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress. FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin. Defects in the FANCD2 gene result in Fanconi anemia complementation group D2. This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FANCD2
Applications Western Blot
Classification Monoclonal
Clone 6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2
Gene FANCD2
Gene Accession No. Q9BXW9
Gene Alias 2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Gene Symbols FANCD2
Host Species Mouse
Immunogen Human FANCD2 fusion protein.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2177
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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