Invitrogen™ FANCM Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103839

Catalog No. PIPA5103839

Description

Antibody detects endogenous levels of total FANCM.

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: FANCM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FANCM
• Gene Alias: AI427100; ATP-dependent RNA helicase FANCM; C730036B14Rik; D12Ertd364e; FAAP250; FANCM; Fanconi anemia complementation group M; Fanconi anemia group M protein; Fanconi anemia group M protein homolog; Fanconi anemia, complementation group M; fanconi anemia-associated polypeptide of 250 kDa; Kiaa1596; Protein FACM; Protein Hef ortholog; RGD1307897
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 104806, 314172, 57697
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8BGE5, Q8IYD8
• Gene Symbols: FANCM
• Immunogen: A synthesized peptide derived from human FANCM(Accession Q8IYD8), corresponding to amino acid residues H447-S497.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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