Invitrogen™ FAP Monoclonal Antibody (D3), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA551179

Catalog No. FEMA551179

Description

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

Specifications

• Antigen: FAP
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: Q12884
• Gene Symbols: FAP
• Immunogen: Recombinant Human FAPa protein, Ile523-Asp760 (Accession #Q12884).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: D3
• Conjugate: Unconjugated
• Gene: FAP
• Gene Alias: 170 kDa melanoma membrane-bound gelatinase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE; Dipeptidyl peptidase FAP; DPPIV; Fap; FAPA; FAPalpha; fibroblast activation protein; fibroblast activation protein alpha; fibroblast activation protein, alpha; gelatine degradation protease FAP; Integral membrane serine protease; post-proline cleaving enzyme; Prolyl endopeptidase FAP; seprase; Serine integral membrane protease; SIMP; Surface-expressed protease
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 100736572, 2191
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid