Invitrogen™ FAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599458

Catalog No. PIPA599458

Description

Antibody detects endogenous levels of total FAP1.

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

Specifications

• Antigen: FAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAP
• Gene Alias: 170 kDa melanoma membrane-bound gelatinase; Antiplasmin-cleaving enzyme FAP, soluble form; APCE; Dipeptidyl peptidase FAP; DPPIV; Fap; FAPA; FAPalpha; fibroblast activation protein; fibroblast activation protein alpha; fibroblast activation protein, alpha; gelatine degradation protease FAP; Integral membrane serine protease; post-proline cleaving enzyme; Prolyl endopeptidase FAP; seprase; Serine integral membrane protease; SIMP; Surface-expressed protease
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14089, 192203, 2191
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P97321, Q12884
• Gene Symbols: FAP
• Immunogen: A synthesized peptide derived from human FAP(Accession Q12884), corresponding to amino acid residues W346-E396.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov