Invitrogen™ FAPP2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518211

Catalog No. PIPA518211

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000. Preliminary analysis showed no signal in Western Blot.

Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.

Specifications

• Antigen: FAPP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLEKHA8
• Gene Alias: 6330400G01; AA517676; BC052360; FAPP2; Fapp-2; hFAPP2; MGC3358; PH domain-containing family A member 8; phosphatidylinositol-four-phosphate adapter protein 2; phosphoinositol 4-phosphate adapter protein 2; pleckstrin homology domain containing A8; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; pleckstrin homology domain-containing family A member 8; PLEKHA8; RGD1563940; Serologically defined breast cancer antigen NY-BR-86
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 84725
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96JA3
• Gene Symbols: PLEKHA8
• Immunogen: Synthetic peptide sequence (DIQTALRNPTENT) corresponding to the C-terminus amino acids of PLEKHA8 (aa 428-434).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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