Invitrogen™ FARS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119903

Catalog No. PIPA5119903

Description

Positive Control: Rat colon tissue lysate, 293T cell lysate, SH-SY5Y, rat testis tissue, human small intestine tissue, mouse cerebellum tissue, SiHa. Subcellular Location: Mitochondrion matrix, Mitochondrion.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS2 is a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS1 encodes a mitochondrially-located phenylalanine-tRNA synthetase (PheRS) which consists of a single polypeptide chain unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and the eukaryotic cytoplasm.

Specifications

• Antigen: FARS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FARS2
• Gene Alias: COXPD14; dJ236A3.1 (phenylalanine-tRNA synthetase); dJ520B18.2; dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase)); Fars1; FARS2; HSPC320; mitochondrial PHERS; pheny; phenylalanine translase; phenylalanine tRNA ligase 2, mitochondrial; phenylalanine--tRNA ligase, mitochondrial; phenylalanine-tRNA synthetase 1 (mitochondrial); phenylalanine-tRNA synthetase 2 (mitochondrial); Phenylalanyl-tRNA synthetase; phenylalanyl-tRNA synthetase 2, mitochondrial; phenylalanyl-tRNA synthetase, mitochondrial; phenylalanyl-tRNA synthetase, mitochondrial; phenylalanine--tRNA ligase, mitochondrial; pheRS
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10667, 306879, 69955
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O95363, Q6AYQ3, Q99M01
• Gene Symbols: FARS2
• Immunogen: Synthetic peptide within human FARS2 aa 50-100/451.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG