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FAS Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501563659
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50-156-3659 20 μL
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Catalog No. 50-156-3659 Supplier Bethyl Laboratories, Inc Supplier No. A302858AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

CD95 (Fas, APO-1), a 46 kDa transmembrane glycoprotein, is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains, formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC, in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis, Fas also triggers pro-inflammatory cytokine responses.

Specifications

Antigen FAS
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene FAS
Gene Accession No. P25445
Gene Alias ALPS1A, APO-1, APT1, Apo-1 Fas, CD95, FAS1, FASTM, TNFRSF6
Gene Symbols FAS
Host Species Rabbit
Immunogen Between 285 and 335
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 355
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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