Invitrogen™ FASN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587440

Catalog No. PIPA587440

Description

Immunogen sequence: QQQTQLNLRS LLVNPEGPTL MRLNSVQSSE RPLFLVHPIE GSTTVFHSLA SRLSIPTYGL QCTRAAPLDS IHSLAAYYID CIRQVQPEGP YRVAGYSYGA CVAFEMCSQL QAQQSPAPTH NSLFLFDGSP TYVLAYTQSY RAKLTPGCEA EAETEAICFF VQQFTDMEHN RVLEALLPLK GLEERVAAAV DLIIKSHQGL DRQELSFAAR SFYYKLRAAE QYTPKAKYHG NVMLLRAKTG GAYGEDLGAD YNLSQVCDGK VSVHVIEGDH RTLLEGSGLE SIISIIHSSL AEPRVSVREG; Positive Samples: H460; Cellular Location: Cytoplasm, Melanosome.

Fatty acid synthase is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Specifications

• Antigen: FASN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FASN
• Gene Alias: [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; A630082H08Rik; Enoyl-[acyl-carrier-protein] reductase; FAS; FASN; Fatty acid synthase; fatty acid synthase (EC 3.2.1.23); MGC14367; MGC15706; OA-519; Oleoyl-[acyl-carrier-protein] hydrolase; SDR27X1; short chain dehydrogenase/reductase family 27X, member 1; thioesterase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2194
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.9 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P49327
• Gene Symbols: FASN
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2212-2511 of human Fatty Acid Synthase (FASN) (NP_0040954).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG