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Invitrogen™ FASTK Monoclonal Antibody (2B7)
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Catalog No. PIMA521195
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100 μg
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Catalog No. Quantity
PIMA521195 100 μg
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Catalog No. PIMA521195 Supplier Invitrogen™ Supplier No. MA521195
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Description

Mouse Monoclonal Antibody

Peptide Sequence: KWGDRPVGGG PSAGPVQGLQ RLLEQAKSPG ELLRWLGQNP SKVRAHHYSV ALRRLGQLLG SRPRPPPVEQ VTLQDLSQLI IRNCPSFD.

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FASTK
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2B7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene FASTK
Gene Accession No. Q14296
Gene Alias 0610011K02Rik; 610011K02Rik; Fas activated serine/threonine kinase; Fas-activated serine/threonine kinase; FAST; FAST kinase; Fastk
Gene Symbols FASTK
Host Species Mouse
Immunogen FASTK (NP_006703, 67 a.a. ~ 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10922
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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