Invitrogen™ FASTK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105266

Catalog No. PIPA5105266

Description

Antibody detects endogenous levels of total FAST kinase.

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

Specifications

• Antigen: FASTK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FASTK
• Gene Alias: 0610011K02Rik; 610011K02Rik; Fas activated serine/threonine kinase; Fas-activated serine/threonine kinase; FAST; FAST kinase; Fastk
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10922, 296741, 66587
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q14296, Q9JIX9
• Gene Symbols: FASTK
• Immunogen: A synthesized peptide derived from human FASTK(Accession Q14296), corresponding to amino acid residues L390-G440.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG