Invitrogen™ FAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554910

Catalog No. PIPA554910

Description

Immunogen sequence: NFQRALRNIL GVRRNDIQIV SLQSSEPHPH LDVLLFVEKP GSAQISTKQL LHKINSSVTD IEEIIGVRIL NVFQKLCAGL DCPWKFCDEK VSVDESVMST HSTARLSFVT PRHHRAAVCL CKEGRCP Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.

This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

Specifications

• Antigen: FAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAT1
• Gene Alias: 2310038E12Rik; AU023433; Cadherin family member 7; cadherin FAT1 isoform +12; cadherin ME5; cadherin-related family member 8; cadherin-related tumor suppressor homolog; CDHF7; CDHR8; FAT; fat 1 cadherin; FAT atypical cadherin 1; FAT tumor suppressor 1; FAT tumor suppressor homolog 1; FAT tumor suppressor homolog 1 (Drosophila); FAT1; Fath; hFat1; ME5; mFat1; Protein fat homolog; protocadherin Fat 1; Protocadherin Fat 1, nuclear form
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2195
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14517
• Gene Symbols: FAT1
• Immunogen: Recombinant protein corresponding to Human FAT1. Recombinant protein control fragment (Product #RP-101000).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov