Invitrogen™ FAT3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550588

Catalog No. PA550588

Description

The antibody detects endogenous levels of total FAT3 protein.

FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system, for example in the brain, it is expressed in a variety of regions and axon fascicles. However, its strongest expression was observed in the olfactory bulb and retina.

Specifications

• Antigen: FAT3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FAT3
• Gene Alias: 9430076A06Rik; Cadherin family member 15; cadherin-related family member 10; CDHF15; CDHR10; D430038H04Rik; FAT atypical cadherin 3; FAT tumor suppressor homolog 3; FAT tumor suppressor homolog 3 (Drosophila); Fat3; Fta3 protein; Gm1132; Gm510; hFat3; KIAA1989; MFAT3F; protocadherin Fat 3; protocadherin Fat3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 120114
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q8TDW7
• Gene Symbols: FAT3
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human FAT tumor suppressor homolog 3 (Drosophila).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG