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Invitrogen™ FAT4 Polyclonal Antibody
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Catalog No. PIPA585904
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100 μL
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PIPA585904 100 μL
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Catalog No. PIPA585904 Supplier Invitrogen™ Supplier No. PA585904
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Rabbit Polyclonal Antibody

FAT4 Polyclonal Antibody for ICC/IF, Western Blot

FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FAT4
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene FAT4
Gene Accession No. Q6V0I7
Gene Alias 6030410K14Rik; 9430004M15; Cadherin family member 14; cadherin-related family member 11; CDHF14; CDHR11; FAT atypical cadherin 4; FAT tumor suppressor homolog 4; FAT tumor suppressor homolog 4 (Drosophila); FAT4; Fatj; FAT-J; fat-like cadherin protein FAT-J; hFat4; HKLLS2; Nbla00548; protocadherin Fat 4; putative protein product of Nbla00548; RGD1564291; VMLDS2
Gene Symbols FAT4
Host Species Rabbit
Immunogen Synthetic peptide within Human FAT tumor suppressor homolog 4 aa 2,264-2,313.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79633
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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