fatty acid elongase Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-4602	100 μL

Catalog No. 50-198-4602 Supplier Bioss Supplier No. BS2260R

Description

Rabbit Polyclonal Antibody

Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.

Specifications

• Antigen: fatty acid elongase
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ELOVL1
• Gene Accession No.: Q9BW60
• Gene Alias: 3-keto acyl-CoA synthase ELOVL1; AA407424; BB151133; CGI88; CGI-88; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1; Elongation of very long chain fatty acids protein 1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; ELOVL1; sequence similarity to Cig30 1; Ssc1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1; very-long-chain 3-oxoacyl-CoA synthase 1
• Gene Symbols: ELOVL1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from Parietochloris incisa fatty acid elongase.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 64834
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG