Invitrogen™ FBLIM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567261

Catalog No. PIPA567261

Description

Immunogen sequence: SKPEKRVASSV FITLAPPRRD VAVAEEVRQA VCEARRGRPW EAPAPMKTPE AGLAGRPSPW TTPGRAAATV PAAPMQLFNG GCPPPPPVLD GE Highest antigen sequence identity to the following orthologs - mouse 63%, rat 67%.

This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: FBLIM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FBLIM1
• Gene Alias: 2410043F08Rik; CAL; CSX-associated LIM; FBLIM1; FBLP1; FBLP-1; filamin binding LIM protein 1; filamin-binding LIM protein 1; filamin-binding LIM protein-1; Gt10; MIG2-interacting protein; migfilin; migfilin(s); mitogen-inducible 2 interacting protein; mitogen-inducible 2-interacting protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54751
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8WUP2
• Gene Symbols: FBLIM1
• Immunogen: Recombinant Human FBLIM1. Recombinant protein control fragment (Product #RP-107897).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov