Invitrogen™ FBP1/FBP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552943

Catalog No. PIPA552943

Description

Immunogen sequence: RKAGLAHLYG IAGSVNVTGD EVKKLDVLSN SLVINMVQSS YSTCVLVSEE NKDAIITAKE KRGKYVVCFD PLDG This product detects both FBP1 and FBP2, which are 80% homologous. The antigen sequence is a 100% match to FBP2 and the product has been validated against FBP1. Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.

FBP1 and FBP2 are gluconeogenesis regulatory enzymes which catalyze the hydrolosis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.

Specifications

• Antigen: FBP1/FBP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FBP1
• Gene Alias: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; FBP; FBP1; FBP2; FBPase 1; FBPase 2; fructose-1; Fructose-1,6-bisphosphatase 1; fructose-1,6-bisphosphatase 2; fructose-1,6-bisphosphatase isozyme 2; fructose-bisphosphatase 1; fructose-bisphosphatase 2; growth-inhibiting protein 17; hexosediphosphatase; liver FBPase; Muscle FBPase; muscle fructose-bisphosphatase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2203, 8789
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O00757, P09467
• Gene Symbols: FBP1, FBP2
• Immunogen: Recombinant protein corresponding to Human FBP2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov