Invitrogen™ FBXL21 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113518

Catalog No. PIPA5113518

Description

FBXL21 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.

Specifications

• Antigen: FBXL21
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FBXL21
• Gene Alias: D630045D17Rik; Fbl21; FBL3B; F-box and leucine rich repeat protein 21 (gene/pseudogene); F-box and leucine-rich repeat protein 21; F-box and leucine-rich repeat protein 3 pseudogene; F-box and leucine-rich repeat protein 3, pseudogene 1; F-box and leucine-rich repeat protein 3B; F-box protein Fbl3b; F-box/LRR-repeat protein 21; F-box/LRR-repeat protein 3B; Fbxl21; Fbxl3b; Fbxl3p; Fbxl3-ps1; Psttm
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 213311, 26223
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 5 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q8BFZ4, Q9UKT6
• Gene Symbols: FBXL21
• Immunogen: Recombinant Human F-box/LRR-repeat protein 21 protein (78-137AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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