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Invitrogen™ FBXO15 Monoclonal Antibody (612834)
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Catalog No. PIMA524277
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Quantity:
100 μg
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Catalog No. Quantity
PIMA524277 100 μg
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Catalog No. PIMA524277 Supplier Invitrogen™ Supplier No. MA524277
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Description

Mouse Monoclonal Antibody

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

F-box protein 15 (FBXO15) is a gene located on chromosome 20p11.1 that encodes a member of the F-box protein family, known for their role in ubiquitin-mediated proteolysis. Proteins in this family contain an F-box domain, enabling them to form part of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which targets specific proteins for ubiquitination and subsequent degradation. FBXO15 is involved in regulating various cellular processes by controlling the turnover of proteins related to cell cycle progression, signal transduction, and development. Its function is crucial for maintaining cellular homeostasis, where dysregulation of FBXO15 can impact protein degradation pathways, potentially leading to disorders such as cancer due to uncontrolled cell proliferation. Current research is focused on understanding the specific targets and functions of FBXO15 within the ubiquitin proteasome system and its potential as a therapeutic target in diseases characterized by aberrant proteolytic activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FBXO15
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone 612834
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene FBXO15
Gene Accession No. Q8NCQ5
Gene Alias AU019763; ecat3; F-box only protein 15; F-box protein 15; FBX15; FBXO15; MGC39671
Gene Symbols FBXO15
Host Species Mouse
Immunogen E. coli-derived recombinant human F-box protein 15/FBXO15 isoform 2 Asn298-Tyr434.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 201456
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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