Invitrogen™ FBXO2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521619

Catalog No. PIPA521619

Description

Recommended positive controls: A431, H1299, HepG2. Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%), Guinea pig (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state.

Specifications

• Antigen: FBXO2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FBXO2
• Gene Alias: FBG1; F-box gene 1; F-box only protein 2; F-box protein 2; Fbs1; Fbs2; FBX2; FBXO2; neural F box protein NFB42; NFB42; OCP1; organ of Corti protein 1; prion protein ligand 4; Prpl4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26232
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9UK22
• Gene Symbols: FBXO2
• Immunogen: Synthetic peptide corresponding to a region within amino acids 234 and 296 of FBXO2 (Uniprot ID#Q9UK22).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG