Invitrogen™ FBXO32 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA519056

Catalog No. PIPA519056

Description

This antibody is predicted to react with bovine, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.

Specifications

• Antigen: FBXO32
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FBXO32
• Gene Alias: 4833442G10Rik; AI430017; atrogin 1; atrogin1; atrogin-1; atrophy gene 1; F-box only protein 32; F-box protein 32; Fbx32; fbxo25; FBXO32; FLJ32424; Gm20361; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein; similar to F-box only protein 32 isoform 1; zgc:56479
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 67731
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9CPU7
• Gene Symbols: FBXO32
• Immunogen: Synthetic peptide sequence (NSKTKTQYFHQEK) corresponding to the internal amino acids of FBXO32 (aa 70-83).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG