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Invitrogen™ FBXO32 Polyclonal Antibody
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Catalog No. PIPA576786
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100 μL
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PIPA576786 100 μL
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Catalog No. PIPA576786 Supplier Invitrogen™ Supplier No. PA576786
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Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FBXO32
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.2
Gene FBXO32
Gene Accession No. Q91Z62, Q969P5, Q9CPU7
Gene Alias 4833442G10Rik; AI430017; atrogin 1; atrogin1; atrogin-1; atrophy gene 1; F-box only protein 32; F-box protein 32; Fbx32; fbxo25; FBXO32; FLJ32424; Gm20361; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein; similar to F-box only protein 32 isoform 1; zgc:56479
Gene Symbols FBXO32
Host Species Rabbit
Immunogen Recombinant full length Human FBXO32.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114907, 171043, 67731
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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