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Invitrogen™ FBXO32 Recombinant Rabbit Monoclonal Antibody (1F10Z5)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA535390
Description
Immunogen sequence: MPFLGQDWRS PGQNWVKTAD GWKRFLDEKS GSFVSDLSSY CNKEVYNKEN LFNSLNYDVA AKKRKKDMLN SKTKTQYFHQ EKWIYVHKGS TKERHGYCTL GEAFNRLDFS TAILDSRRFN.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.
Specifications
FBXO32 | |
Recombinant Monoclonal | |
1.6 mg/mL | |
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q91Z62, Q9CPU7 | |
FBXO32 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Fbx32/FBOX32 (Q969P5). | |
100 μL | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
ELISA, Immunohistochemistry (Paraffin), Western Blot | |
1F10Z5 | |
Unconjugated | |
FBXO32 | |
4833442G10Rik; AI430017; atrogin 1; atrogin1; atrogin-1; atrophy gene 1; F-box only protein 32; F-box protein 32; Fbx32; fbxo25; FBXO32; FLJ32424; Gm20361; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein; similar to F-box only protein 32 isoform 1; zgc:56479 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
171043, 67731 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
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