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Invitrogen™ FBXO33 Polyclonal Antibody
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Catalog No. PIPA589740
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100 μL
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PIPA589740 100 μL
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Catalog No. PIPA589740 Supplier Invitrogen™ Supplier No. PA589740
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VMHKSLDNMP NDEHWKALSR KSTSFRVYIM AFDIKSEDML KILKPSIPLE RIHFDSYITC VSGAIVDLIS RQYDKFLTHF ILMNDVIDTS GFPDLSDNRN EDPLVLLAWR CTKLSLLAIH GYTVWAHNLI AIARLRGSDL KVLEVTEESI DFDQGELADQ DVDPVHNLIE QVSLGLGQPW HAVMDIESLS VFTEPNRHFY REMQSFSEDI; Positive Samples: Rat brain, Rat testis.

FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FBXO33
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Fbxo33
Gene Alias 5730501N20Rik; AI642135; AIG30-12-1; BMND12; c14_5247; F-box only protein 33; F-box protein 33; FBX33; FBXO33
Gene Symbols Fbxo33
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 346-555 of human FBXO33 (NP_9760461).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 314157
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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